A 35-year-old woman is evaluated for a rash on her hands and arms. The previous day she was clearing vines in her backyard. The skin eruption is red and intensely itchy, and she has scratched multiple areas. She experiences a burning sensation when she applies moisturizer. The patient has a history of depression for which she takes sertraline.

On physical examination, vital signs are normal. Skin findings are shown.

The remainder of the examination is unremarkable.

Which of the following is the most appropriate topical therapy for this patient's skin eruption?