A physician has observed that a colleague with whom he has worked for many years has arrived late for and been absent from work with increasing frequency in recent months. While at work, the colleague appears disengaged, distracted, moody, and forgetful. The physician has also noticed lapses in his colleague's judgment and errors which, if unnoticed, might have resulted in patient harm. The physician met with the colleague in private and told him of his observations. He asked his colleague if something is wrong and was rebuffed, being told that he is fine.

Which of the following is the most appropriate course of action for the physician to take regarding his colleague?