A 54-year-old woman is evaluated during a follow-up visit for stage G4/A3 chronic kidney disease due to diabetic nephropathy. She is asymptomatic except for mild fatigue and peripheral edema and reports a good appetite. Medications are ramipril, furosemide, and calcium acetate.

On physical examination, temperature is 37.0 °C (98.6 °F), blood pressure is 128/73 mm Hg, pulse rate is 80/min, and respiration rate is 14/min. BMI is 29. Pallor and pale mucous membranes are noted. There is no jugular venous distention. There is no pericardial friction rub. The lungs are clear. There is no asterixis. Neurologic examination is normal.

Laboratory studies are significant for a serum creatinine level of 2.6 mg/dL (229.8 µmol/L) and an estimated glomerular filtration rate of 19 mL/min/1.73 m2 (1 year ago: 30 mL/min/1.73 m2).

After discussing the goals of care, the patient wishes to explore renal replacement options and kidney transplantation.

Which of the following is the most appropriate management?